How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the κ-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation | ACS Chemical Neuroscience
Frontiers | Modeling the Architecture of Depolymerase-Containing Receptor Binding Proteins in Klebsiella Phages
Lipid Receptor GPR31 (G-Protein–Coupled Receptor 31) Regulates Platelet Reactivity and Thrombosis Without Affecting Hemostasis | Arteriosclerosis, Thrombosis, and Vascular Biology
A plant receptor domain with functional analogies to animal malectin disables ER stress responses upon infection - ScienceDirect
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1 | Journal of Medicinal Chemistry
Inhibition of CSPG receptor PTPσ promotes migration of newly born neuroblasts, axonal sprouting, and recovery from stroke - ScienceDirect
Vaccines | Free Full-Text | Development of a Candidate Multi-Epitope Subunit Vaccine against Klebsiella aerogenes: Subtractive Proteomics and Immuno-Informatics Approach
Ligand with Two Modes of Interaction with the Dopamine D2 Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism | ACS Chemical Neuroscience
Macrophage Scavenger Receptor A Mediates Adhesion to Apolipoproteins A-I and E | Biochemistry
How ligand binds to the type 1 insulin-like growth factor receptor | Nature Communications
Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling - ScienceDirect
Toll-like Receptor 5 Activation by the CagY Repeat Domains of Helicobacter pylori - ScienceDirect
Genes | Free Full-Text | Capturing SNP Association across the NK Receptor and HLA Gene Regions in Multiple Sclerosis by Targeted Penalised Regression Models
Biomolecules | Free Full-Text | Attacking COVID-19 Progression Using Multi-Drug Therapy for Synergetic Target Engagement
Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs | Nature Communications
Discovery of P2Y2 Receptor Antagonist Scaffolds through Virtual High-Throughput Screening | Journal of Chemical Information and Modeling
Probe Confined Dynamic Mapping for G Protein-Coupled Receptor Allosteric Site Prediction | ACS Central Science
Molecules | Free Full-Text | Speculation on How RIC-3 and Other Chaperones Facilitate α7 Nicotinic Receptor Folding and Assembly
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Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation - ScienceDirect
Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses - ScienceDirect
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Discovery of Novel Adenosine Receptor Antagonists through a Combined Structure- and Ligand-Based Approach Followed by Molecular Dynamics Investigation of Ligand Binding Mode | Journal of Chemical Information and Modeling
Molecular dynamics of the histamine H3 membrane receptor reveals different mechanisms of GPCR signal transduction | Scientific Reports
